“Testimony of a strong synergy amongst academia, businesses and independent researchers to fight a global pandemic, Tech Mahindra is also collaborating with a renowned bio-scientist ( Uday Saxena) for plausible therapeutic drugs and research laboratories for synthesizing and testing these compounds,” a press release mentioned.
Tech Mahindra MD and CEO CP Gurnani mentioned COVID-19 continues to disrupt the socio-economic order, impacting lives and livelihood globally.
“As a leading global digital transformation provider, Tech Mahindra is not only committed to ensuring the well-being of our employees, customers and partner ecosystem; but we are also invested in finding a potential cure for COVID-19 by leveraging cutting edge and futuristic technologies like AI,” he mentioned.
Tech Mahindra’s Makers Lab goals to advertise know-how innovation and acknowledge transformative concepts which have a possible to make a distinction and create disruptive options to unravel actual world issues.
The R&D group has used molecular docking method due to excessive transmission charge of COVID-19, the assertion mentioned.
“Our goal was to stop the entry of virus into human host cells akin to lung airway epithelial cells. This is essential as a result of the excessive transmission charges of COVID-19 is attributed partly to the excessive affinity binding and entry of the virus into host cells. Once the virus can’t enter the host cell, it’s innocent,” Nikhil Malhotra, Global Head of Makers Lab mentioned.
He added that the unit’s technique included discovering a GRAS (usually acknowledged as protected) agent which might inhibit the virus and Makers Lab has efficiently utilised two areas of analysis – one is molecular docking on authorized FDA compounds and medicines.
Use of AI helped the analysis group to judge a number of situations with totally different parameters whereas discovering how molecules dock with the principle protease, he mentioned.
The approach, molecular docking, permits seek for therapeutically potent medicine and molecules in actual time, to seek out compounds which might act as inhibitors towards a viral protein computationally.
Tech Mahindra performed molecular docking research throughout 19 FDA (Food and Drug Administration) authorized ligands and anti-viral medicine on the principle protease of the virus, the assertion mentioned.
“There is more work needed to be done to move the process from molecular docking to actual drug design, testing and drug development at scale. This is just the first step, where computational analysis can reduce the amount of time taken to narrow down the search amongst the vast array of molecules present in the process of finding a cure to COVID-19,” it famous.
As a part of the TechMNxt constitution, Tech Mahindra’s Makers Lab is targeted on growing future-ready resolution by leveraging subsequent gen applied sciences akin to AI, Machine Learning, Robotics, Internet of Things (IoT), Augmented Reality/ Virtual Reality and 5G.
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